期刊
Asian Journal of Organic Chemistry
标题
Robust Hydrogenation of Nitrile and Nitro Groups to Primary Amines Using Ni2P as a Catalyst and Ammonia Borane under Ambient Conditions
作者
Yun-Feng Zen, Zi-Cheng Fu, Fei Liang, Yong Xu, Dan-Dan Yang, Zhi Yang, Xin Gan, Zhe-Shuai Lin, Yong Chen, Wen-Fu Fu
摘要
Selective hydrogenation of nitrile groups to primary amines is challenging owing to their high reactivity towards producing secondary and tertiary amines. An unprecedented and efficient system for the hydrogenation of nitrile and nitro groups to primary amines catalyzed by Ni2P nanoparticles in mixed aqueous H3NBH3 solution under ambient conditions is reported. The system exhibits high catalytic selectivity towards generating primary amines, resulting in good isolated yields. Density functional theory calculations rationalize the observed results that composite interactions among species on the catalyst surface alter the catalytic pathway.
原文链接
http://onlinelibrary.wiley.com/doi/10.1002/ajoc.201700584/abstract