期刊

Advanced Functional Materials

标题

Cancer Therapy: Photo-Induced Charge-Variable Conjugated Polyelectrolyte Brushes Encapsulating Upconversion Nanoparticles for Promoted siRNA Release and Collaborative Photodynamic Therapy under NIR Light Irradiation

作者

Hui Zhao, Wenbo Hu, Hengheng Ma, Rongcui Jiang, Yufu Tang, Yu Ji, Xiaomei Lu, Bing Hou, Weixing Deng, Wei Huang, Quli Fan

摘要

In article number 1702592 Quli Fan and co-workers report a photo-induced charge-variable cationic conjugated polyelectrolyte brush encapsulating upconversion nanoparticles (UCNP@CCPEB) for siRNA release and collaborative photodynamic therapy under near-IR light irradiation. With good stability and excellent siRNA-loading capacity, UCNP@CCPEB exhibits good 1O2 production and facilitate siRNA release under 980 nm irradiation, enabling highly effective collaborative tumor therapy in vitro and in vivo

原文链接

http://onlinelibrary.wiley.com/doi/10.1002/adfm.201770264/full