期刊

Advanced Healthcare Materials

标题

Micelles: Multifunctional Polymeric Micelles for Combining Chelation and Detection of Iron in Living Cells

作者

Zhi Liu, Max Purro, Jing Qiao, May P. Xiong

摘要

May P. Xiong and co-workers construct multifunctional Pluronics F127 micelles for iron chelation and fluorescence detection by introducing tetraphenylethene and the chelating drug deferoxamine into self-assembling polymeric micelles in article 1700162. Deferoxamine can simultaneously be used to chelate iron(III) and quench the fluorescence emission of tetraphenylethene. This fluorescence “turn-off” process can be used to monitor the iron chelation process in an iron overload cell model.

原文链接

http://onlinelibrary.wiley.com/doi/10.1002/adhm.201770087/full