期刊

Chemistry – An Asian Journal

标题

Facile Fabrication of Near-Infrared-Responsive and Chitosan-Functionalized Cu2Se Nanoparticles for Cancer Photothermal Therapy (Chem. Asian J. 21/2016) (page 2961)

作者

Zhou Liu, Leung Chan, Liyan Chen, Prof. Yan Bai and Prof. Tianfeng Chen

摘要

Photothermal therapy (PTT) has attracted extensive interest for cancer treatment in the past years. In this study, chitosan (CS)-modified Cu2Se nanoparticles (CS-Cu2Se NPs) were synthesized with the aim to provide cancer chemotherapy and PTT. CS-Cu2Se NPs were found to efficiently convert near-infrared (NIR) light into heat and displayed excellent thermostability. Upon irradiation with a laser they effectively triggered overproduction of intracellular reactive oxygen species (ROS) that promoted cell apoptosis. Therefore, the as-synthesized NPs may find use as anticancer agents for chemotherapy-combined photothermal therapy.

原文链接

http://onlinelibrary.wiley.com/doi/10.1002/asia.v11.21/issuetoc