期刊

Angewandte Chemie

标题
Iridium-Catalyzed Enantioselective Hydroalkynylation of Enamides for the Synthesis of Homopropargyl Amides (Angew. Chem. Int. Ed. 31/2016) (page 8769)

作者
Xiao-Yan Bai, Zi-Xuan Wang and Prof. Dr. Bi-Jie Li

摘要
An Iridium-Catalyzed asymmetric hydroalkynylation of enamides occur regioselectively at the β position of an enamide. In their Communication on page 9007 ff., B.-J. Li and co-workers report a method for the straightforward synthesis of chiral homopropargyl amides with a stereocenter β to the amide. As illustrated in the cover image, enamide and alkyne undergo rapid union to form a chiral product.

原文链接
http://onlinelibrary.wiley.com/doi/10.1002/anie.v55.31/issuetoc