期刊
Advanced Materials

标题
Nanoparticles: Large Pore-Sized Hollow Mesoporous Organosilica for Redox-Responsive Gene Delivery and Synergistic Cancer Chemotherapy (Adv. Mater. 10/2016) (page 2087)

作者
Meiying Wu, Qingshuo Meng, Yu Chen, Lingxia Zhang, Mengli Li, Xiaojun Cai, Yaping Li, Pengcheng Yu, Linlin Zhang and Jianlin Shi

摘要
A stability-difference-selective bond-breakage strategy for the fabrication of largepore-sized hollow mesoporous organosilica nanoparticles (HMONs) is successfully developed. Moreover, surfacefunctionalized HMONs are successfully constructed to simultaneously deliver P-gp modulator siRNA and anticancer drug doxorubicin to reverse the multidrug resistance of cancer cells.

原文链接
http://onlinelibrary.wiley.com/doi/10.1002/adma.201505524/full