期刊
Advanced Materials

标题
Photoacoustic Imaging: In Situ Formation of Nanofibers from Purpurin18-Peptide Conjugates and the Assembly Induced Retention Effect in Tumor Sites (Adv. Mater. 40/2015) (page 6078)

作者
Di Zhang, Guo-Bin Qi, Ying-Xi Zhao, Sheng-Lin Qiao, Chao Yang and Hao Wang

摘要
An assembly-induced retention effect for enhanced tumor photoacoustic (PA) imaging and therapeutics is described. A responsive small-molecule precursor is prepared that simultaneously self-assembles into nanofibers in tumor sites that exhibit an assembly-induced retention effect, which results in an improved PA imaging signal and enhanced therapeutic efficacy. This successful proof-of-concept study paves the way to develop novel supramolecular biomaterials for cancer diagnostics and therapeutics.

原文链接
http://onlinelibrary.wiley.com/doi/10.1002/adma.201502598/full