期刊

Small

标题

Plasmonic Nanostars: In Vivo Volumetric Photoacoustic Molecular Angiography and Therapeutic Monitoring with Targeted Plasmonic Nanostars (Small 8/2014) (page 1441)

作者

Liming Nie, Shouju Wang, Xiaoyong Wang, Pengfei Rong, Ying Ma, Gang Liu, Peng Huang, Guangming Lu and Xiaoyuan Chen

摘要

Induced angiogenesis is a major hallmark of malignant tumor. As reported on page 1585, G. Lu, X. Chen, and co-workers design cyclic Arg-Gly-Asp (RGD) peptide conjugated plasmonic gold nanostars (RGD-GNS) to specifically target integrin avß3 overxpressed on tumor neovasculature. Quantitative volumetric angiography of tumors can be achieved with high resolution and deep penetration by a hemispherical photoacoustic imaging system. It also permits photothermal therapy and sequential therapeutic monitoring.

原文链接

http://onlinelibrary.wiley.com/doi/10.1002/smll.v10.8/issuetoc