期刊

Advanced Functional Materials

标题

Cancer Theranostics: Ultra-Small Iron Oxide Doped Polypyrrole Nanoparticles for In Vivo Multimodal Imaging Guided Photothermal Therapy (Adv. Funct. Mater. 9/2014)(page 1193)

作者

Xuejiao Song, Hua Gong, Shengnan Yin, Liang Cheng, Chao Wang, Zhiwei Li, Yonggang Li, Xiaoyong Wang, Gang Liu and Zhuang Liu

摘要

Polypyrrole (PPy), a NIR-absorbing conjugate polymer, is used by Z. Liu and co-workers to coat iron oxide nanoparticles (IONPs), obtaining IONP@PPy core–shell nanoparticles, further modified by polyethylene glycol. On page 1194, the obtained multifunctional nanoparticles are guided by dual-modal magnetic resonance and photoacoustic imaging for in vivo photothermal therapy, achieving an excellent tumor ablation therapeutic effect in a mouse model. These results promise the use of multifunctional NIR-absorbing organic–inorganic hybrid nanomaterials for applications in cancer theranostics..

原文链接

http://onlinelibrary.wiley.com/doi/10.1002/adfm.v24.9/issuetoc