期刊
Advanced Functional Materials
标题
Mesoporous Nanoparticles: Gated Mesoporous SiO2 Nanoparticles Using K+-Stabilized G-Quadruplexes (Adv. Funct. Mater. 36/2014) (page 5617)
作者
Zhanxia Zhang, Fuan Wang, Yang Sung Sohn, Rachel Nechushtai and Itamar Willner
摘要
On page 5662, I. Willner and team show how K+-ion-stabilized G-quadruplexes act as locks for the entrapment of substrates in mesoporous silica nanoparticles. The pores are unlocked by the Kryptofi × [2.2.2] (KP) through the removal of the K+ ions. Also, programmed duplex structures lock the anticancer drug doxorubicin in mesoporous silica nanoparticles. The pores are unlocked by the separation of the duplex through the formation of a G-quadruplex.
原文链接
http://onlinelibrary.wiley.com/doi/10.1002/adfm.v24.36/issuetoc