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Mesoporous Nanoparticles: Gated Mesoporous SiO2 Nanoparticles Using K+-Stabilized G-Quadruplexes (Adv. Funct. Mater. 36/2014) (page 5617)
时间:2017-01-21 18:58:00
作品信息

期刊

Advanced Functional Materials

标题

Mesoporous Nanoparticles: Gated Mesoporous SiO2 Nanoparticles Using K+-Stabilized G-Quadruplexes (Adv. Funct. Mater. 36/2014) (page 5617)

作者

Zhanxia Zhang, Fuan Wang, Yang Sung Sohn, Rachel Nechushtai and Itamar Willner

摘要

On page 5662, I. Willner and team show how K+-ion-stabilized G-quadruplexes act as locks for the entrapment of substrates in mesoporous silica nanoparticles. The pores are unlocked by the Kryptofi × [2.2.2] (KP) through the removal of the K+ ions. Also, programmed duplex structures lock the anticancer drug doxorubicin in mesoporous silica nanoparticles. The pores are unlocked by the separation of the duplex through the formation of a G-quadruplex.

原文链接

http://onlinelibrary.wiley.com/doi/10.1002/adfm.v24.36/issuetoc

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