期刊
Advanced Functional Materials
标题
Drug Delivery: Gel–Liposome-Mediated Co-Delivery of Anticancer Membrane-Associated Proteins and Small-Molecule Drugs for Enhanced Therapeutic Efficacy (Adv. Funct. Mater. 16/2014)
作者
Tianyue Jiang,Ran Mo,Adriano Bellotti,Jianping Zhou,Zhen Gu
摘要
Sequential and site-specific co-delivery of two anticancer therapeutics in a programmed manner is demonstrated by J. Zhou, Z. Gu, and co-workers on page 2295. The delivery is triggered by the tumor microenvironment and cellular conditions. The gel-liposome based nanovehicle can transport and release an anticancer cytokine (TRAIL) and small-molecule drug (doxorubicin) to their distinct acting sites: the cellular membrane and nucleus
原文链接
http://onlinelibrary.wiley.com/doi/10.1002/adfm.201470099/abstract