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Tumor Margin Demarcation and Therapy: A NanoFlare‐Based Strategy for In Situ Tumor Margin Demarcation and Neoadjuvant Gene/Photothermal Therapy
时间:2018-12-26 13:49:00
分类:Small
作品信息

期刊

Small

标题

Tumor Margin Demarcation and Therapy: A NanoFlare‐Based Strategy for In Situ Tumor Margin Demarcation and Neoadjuvant Gene/Photothermal Therapy

作者

Rong Yan, Jie Chen, Jianhao Wang, Jiaming Rao, Xuancheng Du, Yongming Liu, Leshuai Zhang, Lin Qiu, Bo Liu, Yuan‐Di Zhao, Pengju Jiang, Chunying Chen, Yong‐Qiang Li

摘要

In article number 1802745, Yong‐Qiang Li and co‐workers report a robust tumor microenvironment‐responsive theranostic nanoprobe (NanoFlare). By virtue of its anisotropic oligonucleotides‐spike nanostructure, the NanoFlare can enter tumor cells universally regardless of cell type and produce a redox‐activated fluorescence signal. The NanoFlare enables accurate intraoperative margin demarcation of different tumors and efficient gene/photothermal neoadjuvant therapy in vivo.

原文链接

https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.201870245

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