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Cancer Immunotherapy: Designing Bioinspired 2D MoSe2 Nanosheet for Efficient Photothermal‐Triggered Cancer Immunotherapy with Reprogramming Tumor‐Associated Macrophages
时间:2019-08-16 14:02:27
作品信息

期刊

Advanced Functional Materials

标题

Cancer Immunotherapy: Designing Bioinspired 2D MoSe2 Nanosheet for Efficient PhotothermalTriggered Cancer Immunotherapy with Reprogramming TumorAssociated Macrophages

作者

Lizhen He, Tianqi Nie, Xiaojun Xia, Ting Liu, Yanyu Huang, Xiaojuan Wang, Tianfeng Chen

摘要

In article number 1901240, Tianfeng Chen and co‐workers design bioinspired 2D MoSe2 nanosheets with high photothermal conversion efficiency to achieve efficient photothermal‐triggered cancer immunotherapy, by activating cytotoxic T lymphocytes, reprogramming tumor associated macrophages to a tumoricidal M1 phenotype, and inactivation of the PD‐1/PD‐L1 pathway to avoid immunologic escape.

原文链接

https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201970210

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