期刊

Advanced Materials

标题

Neural Regeneration: Efficient Delivery of Nerve Growth Factors to the Central Nervous System for Neural Regeneration

作者

Duo Xu, Di Wu, Meng Qin, Lina R. Nih, Chaoyong Liu, Zheng Cao, Jie Ren, Xiangjun Chen, Zhanlong He, Wenhai Yu, Jiaoqiong Guan, Suqin Duan, Fang Liu, Xiangsheng Liu, Jesse Li, Dushawn Harley, Bin Xu, Lihua Hou, Irvin S. Y. Chen, Jing Wen, Wei Chen, Sina Pourtaheri, Yunfeng Lu

摘要

Neurotrophins are promising candidates for central nervous system (CNS) diseases and injuries, while their inability to enter the CNS remains a bottleneck for therapeutic purposes. In article number 1900727, Jing Wen, Wei Chen, Sina Pourtaheri, Yunfeng Lu, and co‐workers report a nanocapsule‐based delivery strategy, which enables the efficient entry of nerve growth factors (NGFs) to the CNS. In mice with spinal cord injuries, the effective delivery of NGF promotes neural regeneration, tissue remodeling, and functional recovery.

原文链接

https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201970233