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Extracellular Delivery: Tumor Microenvironment‐Tailored Weakly Cell‐Interacted Extracellular Delivery Platform Enables Precise Antibody Release and Function
时间:2019-12-16 14:35:46
作品信息

期刊

Advanced Functional Materials

标题

Extracellular Delivery: Tumor Microenvironment‐Tailored Weakly Cell‐Interacted Extracellular Delivery Platform Enables Precise Antibody Release and Function

作者

Sidi Li, Luyang Chen, Kai Huang, Ning Chen, Qi Zhan, Kaikai Yi, Hongzhao Qi, Chaoyong Liu, Yanli Tan, Xin Hou, Yunfeng Lu, Jin Zhao, Xubo Yuan, Chunsheng Kang

摘要

In article number 1903296, Jin Zhao, Xubo Yuan, Chunsheng Kang, and co‐workers report a weakly cell‐interacted, nanosized, environment‐responsive delivery platform (WINNER) for precise extracellular release of extracellularly functional protein drugs. The WINNER can protect the inner drugs from cellular uptake and undergo enzymatic degradation in the tumor microenvironment to uncage the therapeutic power of the therapeutic agents.

原文链接

https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201970301

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