Advanced Functional Materials
Extracellular Delivery: Tumor Microenvironment‐Tailored Weakly Cell‐Interacted Extracellular Delivery Platform Enables Precise Antibody Release and Function
Sidi Li, Luyang Chen, Kai Huang, Ning Chen, Qi Zhan, Kaikai Yi, Hongzhao Qi, Chaoyong Liu, Yanli Tan, Xin Hou, Yunfeng Lu, Jin Zhao, Xubo Yuan, Chunsheng Kang
In article number 1903296, Jin Zhao, Xubo Yuan, Chunsheng Kang, and co‐workers report a weakly cell‐interacted, nanosized, environment‐responsive delivery platform (WINNER) for precise extracellular release of extracellularly functional protein drugs. The WINNER can protect the inner drugs from cellular uptake and undergo enzymatic degradation in the tumor microenvironment to uncage the therapeutic power of the therapeutic agents.