期刊

Advanced Science

标题

Cell‐Free Protein Synthesis: A Cell‐Free Platform Based on Nisin Biosynthesis for Discovering Novel Lanthipeptides and Guiding their Overproduction In Vivo

作者

Ran Liu, Yuchen Zhang, Guoqing Zhai, Shuai Fu, Yao Xia, Ben Hu, Xuan Cai, Yan Zhang, Yan Li, Zixin Deng, Tiangang Liu

摘要

In article number 2001616, Tiangang Liu and co‐workers develop a cell‐free protein synthesis (CFPS) platform that enables rapid discovery of novel lanthipeptides and guides lanthipeptide overproduction in vivo. This study extends the use of cell‐free systems to address the issue facing lanthipeptide research, while providing the possibility for developing CFPS platforms for other ribosomally synthesized and post‐translationally modified peptides studies.

原文链接

https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202070096