期刊
Advanced Materials
标题
Cation-Free siRNA Micelles as Effective Drug Delivery Platform and Potent RNAi Nanomedicines for Glioblastoma Therapy
作者
Tong Jiang,Yonghan Qiao,Weimin Ruan,Dongya Zhang,Qingshan Yang,Guoying Wang,Qunzhi Chen,Fengping Zhu,Jinlong Yin,Yan Zou,Rongjun Qian,Meng Zheng,Bingyang Shi
摘要
Tumor Therapy
In article number 2104779, Meng Zheng, Bingyang Shi, and co-workers develop a kind of polymeric siRNA micelle as an effective drug-delivery platform and potent RNAi nanomedicine for glioblastoma therapy. The siRNA micelles are capable of traversing the blood–brain barrier via transcytosis mediated by scavenger receptors, to subsequently target a brain tumor and then exert potent RNAi therapy or RNAi-Chemo synergistic therapy.
原文链接