期刊

Chemical Communications

标题

Visible-light photocatalytic bicyclization of β-alkynyl propenones for accessing diastereoenriched syn-fluoren-9-ones

作者

Zheng-Jia Shen, Hao-Nan Shi, Wen-Juan Hao, Shu-Jiang Tu and  Bo Jiang 

摘要

A novel visible-light photocatalytic bicyclization of β-alkynyl propenones with α-bromocarbonyls for highly diastereoselective synthesis of richly decorated syn-fluoren-9-ones is described. The reaction proceeds via a radical-triggered 5-exo-dig cyclization/1,6-H-abstraction/6-endo-trig cyclization cascade and offers a new and practical method for the assembly of 6/5/6 carbocyclic skeletons via C(sp3)–H alkenylation.

原文链接

https://pubs.rsc.org/en/content/articlelanding/2018/cc/c8cc06086j