期刊
Exploration
标题
Frontispiece: Rational design of allosteric switchable catalysts
作者
Tiezheng Pan,Yaling Wang,Xue Xue,Chunqiu Zhang
摘要
Toolbox of allosteric catalysts
Allosteric regulation that controls the activities of natural enzymes motivates the exploration of expanded toolbox of switchable catalysts for chemical biology research. This review presents prospects of how allosteric scaffolds, ranging from single molecules to self-assemblies, could be designed into artificial switchable catalysts. The strategy of conformation-catalysis synergistics provides great inspirations and opportunities for fundamental research and biomedical applications.
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