期刊
Advanced Science
标题
Intravital Whole-Process Monitoring Thermo-Chemotherapy Via 2D Silicon Nanoplatform: A Macro Guidance and Long-Term Microscopic Precise Imaging Strategy
作者
Doudou Huang, Guangxing Wang, Jingsong Mao, Chunlei Liu, Zhongxiong Fan, Yunrui Zhang, Bei Zhang, Yang Zhao, Cuixia Dai, Yaqin He, Heng Ma, Gang Liu, Xiaoyuan Chen, Qingliang Zhao
摘要
Thermo-Chemotherapy
A promising biocompatible nanotheranostics agent based on chemotherapeutic drug 5-fluorouracil and 2D silicon nanosheets is developed for synergistic thermo-chemotherapy strategy. The tumor tissue functional parameters, including SaO2, HbT, micro microvascular morphology, and hemodynamics, are dynamically monitored by multimodal PA/OCTA/LS imaging strategy to accurately evaluate overall therapeutic effects. This novel strategy exhibits prominent therapeutic efficiency on malignant glioma U87-MG. More details can be found in article number 2101242 by Heng Ma, Qingliang Zhao, and co-workers.
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