期刊
Molecular Nutrition & Food Research
标题
Soyasaponin A2 Alleviates Steatohepatitis Possibly through Regulating Bile Acids and Gut Microbiota in the Methionine and Choline-Deficient (MCD) Diet-induced Nonalcoholic Steatohepatitis (NASH) Mice
作者
Lihua Han, Min Du, Fazheng Ren, Xueying Mao
摘要
Mol. Nutr. Food Res. 2021, 65, 2001208
Maternal polar lipids-enriched milk fat globule membrane supplementation to high-fat diet (HFD) dams throughout pregnancy and lactation facilitates bone development of male offspring at weaning and protects against HFD-induced bone loss at adulthood. The alleviated hypothalamic insulin resistance, increased hypothalamic GHRH expression and subsequently enhanced GH/IGF-1 axis activity partially contribute to the lasting beneficial programming impacts on skeletal outcomes of male offspring. This is reported by Xueying Mao and co-workers in article number 2001208.
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