期刊
Advanced Functional Materials
标题
Immunostimulant In Situ Hydrogel Improves Synergetic Radioimmunotherapy of Malignant Glioblastoma Relapse Post-Resection
作者
Shuo Sun,Wei Gu,Haisi Wu,Qianqian Zhao,Shiyu Qian,Hong Xiao,Kun Yang,Jian Liu,Yu Jin,Chupeng Hu,Ye Gao,Huae Xu,Hongyi Liu,Jing Ji,Yun Chen
摘要
Flexible Optoelectronics
In article number 2205038, Huae Xu, Hongyi Liu, Jing Ji, Yun Chen, and co-workers present an injectable, reactive oxygen species-responsive therapeutic hydrogel (ADU-AAV-PD1@Gel), capable of sustained local release of soluble PD-1 (sPD-1) and STING agonist ADU-S100. The ADU-AAV-PD1@Gel combined with radiotherapy generates a robust antitumor immune response and induces long-term immune memory to prevent glioblastoma recurrence.
原文链接
