期刊
Molecular Nutrition & Food Research
标题
Diallyl Trisulfide Prevents Adipogenesis and Lipogenesis by Regulating the Transcriptional Activation Function of KLF15 on PPARγ to Ameliorate Obesity
作者
Yanzhou Hu, Jia Xu, Ruxin Gao, Ye Xu, Bingxin Huangfu, Charles Asakiya, Xianghui Huang, Feng Zhang, Kunlun Huang, Xiaoyun He, Yunbo Luo
摘要
Mol. Nutr. Food Res. 2022, 66, 2200173
Diallyl trisulfide (DATS), a bioactive compound in garlic, reduces lipid accumulation and ameliorates diet-induced obesity. DATS prevents adipogenesis and lipogenesis by inhibiting the binding of KLF15 to PPARγ gene promoter. This is reported by Yunbo Luo, Xiaoyun He, and co-workers in article number 2200173.
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