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Diallyl Trisulfide Prevents Adipogenesis and Lipogenesis by Regulating the Transcriptional Activation Function of KLF15 on PPARγ to Ameliorate Obesity
时间:2022-11-28 13:41:24
作品信息

期刊

Molecular Nutrition & Food Research

标题

Diallyl Trisulfide Prevents Adipogenesis and Lipogenesis by Regulating the Transcriptional Activation Function of KLF15 on PPARγ to Ameliorate Obesity

作者

Yanzhou Hu, Jia Xu, Ruxin Gao, Ye Xu, Bingxin Huangfu, Charles Asakiya, Xianghui Huang, Feng Zhang, Kunlun Huang, Xiaoyun He, Yunbo Luo

摘要

Mol. Nutr. Food Res. 2022, 662200173

DOI: 10.1002/mnfr.202200173

Diallyl trisulfide (DATS), a bioactive compound in garlic, reduces lipid accumulation and ameliorates diet-induced obesity. DATS prevents adipogenesis and lipogenesis by inhibiting the binding of KLF15 to PPARγ gene promoter. This is reported by Yunbo Luo, Xiaoyun He, and co-workers in article number 2200173.

原文链接
https://onlinelibrary.wiley.com/doi/10.1002/mnfr.202270059

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