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Kartogenin-Conjugated Double-Network Hydrogel Combined with Stem Cell Transplantation and Tracing for Cartilage Repair
时间:2023-01-09 16:52:25
作品信息

期刊

Advanced Science

标题

Kartogenin-Conjugated Double-Network Hydrogel Combined with Stem Cell Transplantation and Tracing for Cartilage Repair

作者

You-Rong Chen, Xin Yan, Fu-Zhen Yuan, Lin Lin, Shao-Jie Wang, Jing Ye, Ji-Ying Zhang, Meng Yang, De-Cheng Wu, Xing Wang, Jia-Kuo Yu

摘要

Cartilage Regeneration

PEG-CHI-KGN DN gel combined with peripheral blood-derived mesenchymal stem cells (PB-MSCs) is employed in treating knee cartilage defects. Compared with current tissue-engineering products, it has unique strength because of optimized mechanics, high biosafety, and a simple preparation process. PEG-CHI-KGN DN gel promote the chondrogenic differentiation and survival of allogenic PB-MSCs, ultimately enhancing cartilage regeneration and providing an innovative clinical treatment strategy from the tissue-engineering perspective. More details can be found in article number 2105571 by De-Cheng Wu, Xing Wang, Jia-Kuo Yu, and co-workers.

原文链接

https://onlinelibrary.wiley.com/doi/10.1002/advs.202270225

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