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Innenrücktitelbild: Endogenous Enzyme-Operated Spherical Nucleic Acids for Cell-Selective Protein Capture and Localization Regulation
时间:2023-05-04 14:37:29
作品信息

期刊

Angewandte Chemie

标题

Innenrücktitelbild: Endogenous Enzyme-Operated Spherical Nucleic Acids for Cell-Selective Protein Capture and Localization Regulation

作者

Dr. Qing Liu, Yuanyu Huang, Prof. Lele Li, Prof. Zhengping Li, Mengyuan Li

摘要

Cell-selective regulation of protein translocation is achieved through the rational design of an endogenous enzyme-operated spherical nucleic acids platform. The system enables enzyme-activated capture of proteins of interest and thus regulation of their cytoplasmic-nuclear shuttling with tumor-cell specificity, as reported by Mengyuan Li and co-workers in their Research Article (e202214958).

原文链接

https://onlinelibrary.wiley.com/doi/10.1002/anie.202303991

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