期刊
Advanced Functional Materials
标题
Micropattern-Based Stem Cell Gym: Mechanical Memory Enhanced Stemness Maintenance of Human Dental Pulp Stem Cells and Nerve Regeneration
作者
Chiyu Li, Fanqi Meng, Zhijie Yang, Jiang Peng, Yuwei Guo, Jing Na, Qiusheng Shi, Yu Liu, Yu Wang, Lisha Zheng, Yubo Fan
摘要
Stem Cell Gym
In article number 2302829, Yu Wang, Lisha Zheng, Yubo Fan, and co-workers develop a micropatterned based stem cell gym to train dental pulp stem cells for stemness maintenance. The micropattern based gym with 1024 μm2 and aspect ratios of 1:2 and 1:4 effectively enhances the stemness and rescues the pluripotency of stem cells during long-term expansion. The stem cell gym-induced mechanical memory also promotes nerve regeneration in vivo.
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