期刊
Small Science
标题
Binding of Perfluoroalkyl Substances to Nanoplastic Protein Corona Is pH-Dependent and Attenuates Their Bioavailability and Toxicity
作者
Zongshan Zhao, Jiaqiang Yao, Haimei Li, Jing Lan, Yan Bao, Lining Zhao, Wansong Zong, Yanmin Long, Lei Feng, Henner Hollert, Xingchen Zhao
摘要
Nanoplastics
Nanoplastics serve as vectors for perfluoroalkyl pollutants in biological fluids, influencing protein binding behavior. Low pH weakens PFOS interactions while leaving PFOA unaffected, with PFOS still exhibiting greater serum persistence. Additionally, nanoplastics and serum albumin lower the cellular uptake and cytotoxicity of perfluoroalkyls by reducing their bioavailability. More in article number 2400255, Xingchen Zhao and co-workers.
原文链接
