期刊

Angewandte Chemie

标题

Inside Cover: Two-Way Nanopore Sensing of Sequence-Specific Oligonucleotides and Small-Molecule Targets in Complex Matrices Using Integrated DNA Supersandwich Structures (Angew. Chem. Int. Ed. 7/2013) (page 1842)

作者

Nannan Liu, Yanan Jiang, Yahong Zhou, Prof. Fan Xia, Dr. Wei Guo and Prof. Lei Jiang

摘要

DNA supersandwich structures work as gatekeepers for solid-state nanopores as part of a target-specific nanofluidic sensor for both oligonucleotides and small molecules, as shown by F. Xia, W. Guo et al. in their Communication on page 2007 ff. The DNA superstructures enhance the sensitivity and reduce the background signal, so that the biohybrid nanodevice also works well in complex mixtures, such as mammalian serum.

原文链接

http://onlinelibrary.wiley.com/doi/10.1002/anie.v52.7/issuetoc