当前位置: 首页 > 学术作品
Electrochemical Synthesis of (Aza)indolines via Dehydrogenative [3+2] Annulation: Application to Total Synthesis of (±)-Hinckdentine A
时间:2022-01-18 14:00:26
作品信息

期刊

Chinese Journal of Chemistry

标题

Electrochemical Synthesis of (Aza)indolines via Dehydrogenative [3+2] Annulation: Application to Total Synthesis of (±)-Hinckdentine A

作者

Zhong-Wei Hou, Hong Yan, Jin-Shuai Song, Hai-Chao Xu

摘要

The cover picture shows an electricity powered dehydrogenative [3+2] annulation reaction of (hetero)arylamines with tethered di-, tri, and tetra-substituted alkenes for the preparation of indoline and azaindoline products. The electrochemical reactions proceed through H2 evolution and thus avoid the use of stoichiometric chemical oxidants. This method, which is applicable to the preparation of highly functionalized (aza)indoline scaffold, enables the total synthesis of (±)-hinckdentine A in 12 steps. More details are discussed in the article by Xu et al. on page 909–915.

原文链接

https://onlinelibrary.wiley.com/doi/10.1002/cjoc.201880101

在线咨询
ONLINE CONSULTING
电话咨询
PHONE CONSULTING

010-82449939