期刊

Chemical Communications

标题

Bacteria mimics bearing carbohydrates, oligodeoxynucleotides and designed shapes

作者

Jun Hu, Yan Gu, Mengjie Liu, Weidong Zhang, Hong Chen and Gaojian Chen

摘要

We utilize a facile and gentle strategy to fabricate bacteria mimics (“bacillus” and “coccus”) endowed with carbohydrates, oligodeoxynucleotides and designed shapes via dopamine-polymer based nanoparticle fabrication and DNA-based multivalent interactions. These bacteria mimics with TLR- and CLR-targeted capabilities are demonstrated to exhibit enhanced immune stimulating efficiency.

原文链接

https://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc02239j