期刊
Advanced Materials
标题
Circadian Clock Regulation via Biomaterials for Nucleus Pulposus
作者
Wei Chen, Dandan Zheng, Hao Chen, Tingjun Ye, Zhihong Liu, Jin Qi, Hongxing Shen, Huitong Ruan, Wenguo Cui, Lianfu Deng
摘要
Tissue Regeneration
Inspired by the regulation of cellular circadian clock on tissue regeneration, in article number 2301037, Huitong Ruan, Wenguo Cui, Lianfu Deng, and co-workers report circadian-clock-regulating biomaterials that are fabricated using the air-microfluidic technique. The chemical cross-linking between poly(vinyl alcohol) and modified phenylboronic acid can effectively activate the intrinsic circadian clock of nucleus pulposus cells via the PI3K-AKT pathway, thus improving the regeneration of intervertebral discs.
原文链接
